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The link between heart failure and CFS

Wednesday 6 January 2010's Adrienne Dellwo reports on results of recent studies that show "cardiac irregularites" in people with ME/CFS:

The Link Between Heart Failure & Chronic Fatigue Syndrome

Wednesday December 30, 2009

Research Brief

Two studies recently published in Neuroendocrinology Letters suggest underlying factors of the cardiovascular irregularities some research has linked to chronic fatigue syndrome (CFS or ME/CFS).

CoQ10 Study

The first looked at CoQ10 levels between 58 people with ME/CFS and 22 healthy people. It was significantly low in those with ME/CFS and was a predictor of how severe symptoms were, especially concentration and memory problems (brain fog.)

Other research has suggested that low CoQ10 is a predictor of chronic heart failure (CHF), and researchers say this could help explain the link between ME/CFS and CHF. A 2006 study indicated that people with both ME/CFS and CHF die an average of 25 years earlier than people with just CHF.

Researchers suggest CoQ10 supplementation for those with ME/CFS, and they add that since statins (cholesterol drugs) lower CoQ10, people with ME/CFS shouldn't take statins without CoQ10 supplementation.

Inflammation, Oxidative & Nitrosative Stress Study

Following up on the 2006 study mentioned above, researchers reviewed available literature looking for a possible explanation of earlier death due to CHF (mean age 59 for ME/CFS, age 83 for others.)

Researchers identified 6 possible contributing factors. (I've kept this list as simple as possible; those well versed in medical terminology can click on the heading above for more in-depth information.)

  1. Effects of chronic low grade inflammation
  2. Increased oxidative and nitrosative stress
  3. Low levels of antioxidants CoQ10, zinc and DHEA-sulphate
  4. Spread of bacteria due to leaky gut
  5. Low omega-3 fatty acids, high omega-6 and saturated fat
  6. Viral and bacterial infections and psychological stressors (This is the researchers' grouping, not mine.)

Researchers conclude that these abnormalities may increase the risk of heart problems in people with ME/CFS.

The above originally appeared here.



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