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Treatment of CFS: Findings, Principles and Strategies

Friday 8 January 2010

ResearchPubMed has published the following:

Psychiatry Investig. 2008 December; 5(4): 209–212.
PMCID: PMC2796012
Published online 2008 December 31. doi: 10.4306/pi.2008.5.4.209.

Copyright © 2008 Official Journal of Korean Neuropsychiatric Association

Treatment of Chronic Fatigue Syndrome: Findings, Principles and Strategies

Patrick Luyten, PhD,corresponding author1 Boudewijn Van Houdenhove, MD, PhD,2 Chi-Un Pae, MD, PhD,3,4 Stefan Kempke, MA,1 and Peter Van Wambeke, MD, PhD2

1Department of Psychology, University of Leuven, Leuven, Belgium.
2University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium.
3Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, Korea.
4Department of Psychiatry and Behavioral Sciences, Duke University Medical University, Durham, NC, USA.
corresponding authorCorresponding author.
Correspondence: Patrick Luyten, PhD. Department of Psychology, University of Leuven, Tiensestraat 102, 3000 Leuven, Belgium. Tel +32-1-632-6135, Fax +32-2-770-6972, Email:

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Chronic fatigue syndrome (CFS) is a debilitating condition characterized by serious medically unexplained mental and physical fatigue. The high prevalence and both direct and indirect health costs of CFS patients represent a huge problem for contemporary health care. Moreover, the prognosis of CFS, even when treated, is often poor. In this paper, we first critically review current evidence based treatments of CFS. Second, we discuss the growing insights into the etiopathogenesis of CFS, and the need to translate and integrate these insights into future treatments. In particular, we formulate a pragmatic and empirically testable treatment approach, tailored to the individual needs of patients, which aims at restoring the mental and physical equilibrium of CFS patients by trying to bring about sustained life style changes.

Keywords: Chronic fatigue syndrome, Treatment

The abstract can be found here.

The full text can be found here.



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