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Cognitive functioning in CFSFriday 22 January 2010
Cognitive functioning in Chronic Fatigue Syndrome: A meta-analysis – Source: Psychological Medicine, Jan 2010 by SJ Cockshell, JL Mathias Background: Cognitive problems are commonly reported in persons with chronic fatigue syndrome (CFS) and are one of the most disabling symptoms of this condition. A number of cognitive deficits have been identified, although the findings are inconsistent and hindered by methodological differences. The current study therefore conducted a meta-analysis of research examining cognitive functioning in persons with CFS in order to identify the pattern and magnitude of any deficits that are associated with this condition. Method: A comprehensive search of the PubMed and PsycINFO databases for studies that examined cognitive functioning in CFS between 1988 and 2008 identified 50 eligible studies. Weighted Cohen's d effect sizes, 95% confidence intervals and fail-safe Ns were calculated for each cognitive score. Results: • Deficits were not apparent on tests of fine motor speed, vocabulary, reasoning and global functioning. Conclusions: Persons with CFS demonstrate moderate to large impairments: • In simple and complex information processing speed, • And in tasks requiring working memory over a sustained period of time. Source: Psychological Medicine, Jan 5, 2010.pp 1-15. PMID: 20047703, by Cockshell SJ, Mathias JL. School of Psychology, The University of Adelaide, South Australia, Australia. [E-mail: jane.mathias@psychology.adelaide.edu.au]. The above originally appeared here.
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