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Patients' Reanalysis Sinks PACE's "Recovery" Claims
Thursday 22 September 2016
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PATIENTS’ REANALYSIS SINKS PACE’S “RECOVERY” CLAIMS
New research finds a striking similarity
Patients and statisticians have used the recently released data from the PACE trial to show that cognitive behavioural therapy and graded exercise therapy did not help patients in the study to recover.
Alem Matthees, an Australian patient who obtained the data after a two-year battle over his Freedom of Information request, applied the study authors’ own pre-planned analyses that they had abandoned after the trial had finished.
Working with independent statisticians and other patients with mathematical expertise, he showed that only 7% of the cognitive behavioural therapy group, 4% of the graded exercise group, and 3% of a no-therapy comparison group recovered. Differences between the groups were within chance variation, indicating no effect of the therapies.
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