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Dr. Anthony Komaroff's Responses To Follow-Up Webinar Questions

Friday 18 November 2016


From the Solve ME/CFS Initiative:


Dr. Anthony Komaroff
Dr. Anthony Komaroff

Dr. Anthony Komaroff’s Responses to Follow-Up Webinar Questions

Wednesday, November 16, 2016

On November 10, the Solve ME/CFS Initiative hosted a webinar with Dr. Anthony L. Komaroff, Simcox-Clifford-Higby professor of medicine at Harvard Medical School and senior physician at Brigham and Women’s Hospital in Boston, Massachusetts. Dr. Komaroff has followed up with his responses to the numerous questions that were unable to be answered during the webinar due to time limitations. To watch the full video of the webinar, go here.

Q: To what extent are different researchers with their different focuses converging on a single, generally agreed explanation for the cause of ME/CFS and the mechanism or mechanisms that maintain it?

A: Abnormalities involving multiple organ systems have been identified, and there are theories that could tie together many of those abnormalities, but proving any of those theories is going to take much more work. In the Webinar, I discussed one theory, about how low-grade inflammation in the brain, or inflammation elsewhere in the body that could theoretically lead to low-grade inflammation in the brain, could be responsible for the symptoms of ME/CFS.

Q: How soon will we see approved drug treatments, and which will be the first to be approved?

A: For drug companies to pursue a drug for ME/CFS, they need a target for their drug to shoot at. While many different biological abnormalities have been reported in people with ME/CFS, it’s not clear which are central to the illness―and, therefore, good targets.


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