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Response To Commentary: 'Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, And Chronic Fatigue: Three Distinct Entities Requiring Complete Different Approaches'

Thursday 11 April 2019


From Current Rheumatology Reports:



Response to Commentary: ‘Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, and Chronic Fatigue: Three Distinct Entities Requiring Complete Different Approaches’

Letter to the Editor
First Online: 6 April 2019
© Springer Science+Business Media, LLC, part of Springer Nature 2019

We are surprised by the nature of the comments we have received primarily addressing the differences between myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS), which was neither the focus, nor intended topic, of our article ‘The invisible burden of chronic fatigue in the community: A narrative review’ []. Rather, the intention of our review was to highlight the importance of investigating individuals in the community suffering from prolonged fatigue or chronic fatigue who have long been overlooked.

Does it really matter whether ME and CFS are synonymous labels or not? Both labels refer to an illness with heavily overlapping subjective symptom criteria and require a 6 months diagnosis. Given that both labels require the symptoms to be present for 6 months, individuals with the ME and CFS diagnostic label must initially have had a period of symptoms shorter than 6 months. Prolonged fatigue is defined as medically unexplained, debilitating fatigue that persists for 1 to 6 months []. Therefore, everyone who received a diagnosis of ME and CFS at 6 months must have suffered initially with prolonged fatigue, a condition that is poorly understood and understudied.


Full article…



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